Endotoxins are toxic substances found in the outer membrane of gram-negative bacteria. When these bacteria die, endotoxins are released, triggering inflammatory responses in the host.
Key Points:
- Composition: Endotoxins are primarily lipopolysaccharides (LPS) and form part of the bacterial cell wall.
- Immune Response: They can cause symptoms like fever and inflammation, and in severe cases, lead to septic shock.
Importance:
- Health Effects: Elevated endotoxin levels can contribute to chronic inflammation and serious health issues.
- Gut Health: Increased intestinal permeability can allow endotoxins to enter the bloodstream, leading to systemic inflammation.
Reducing Exposure:
- Diet: A balanced diet rich in fiber, probiotics, and anti-inflammatory foods can help reduce endotoxin absorption.
- Probiotics: Certain probiotic strains may support gut barrier function and modulate the immune response.